Department: Animal Reproduction
Objectives: The awareness of factors determining morphological and physiological phenotypes has evolved in the last years from genome to a more complicated concept (developmental programming) in which prenatal and postnatal environmental conditions markedly modify the epigenotype, and therefore the phenotype and homeostasis of the individuals, and determine their juvenile growth, life-time fitness and disease risks. These process are maintained in different mammal species, which allow the possibility of modelling among them; the choice of the model depending on the research objectives and on the availability of the animal models. Hence, the objective of the group is to study the developmental origins of physiological/pathological features of mammalian species by using rabbits, ruminants and swine as translational models.
Key words: developmental programming, environmental effects, embryo, foetus, genetic and epigenetic regulation, prenatal and postnatal development.
- Nombre:Antonio Gonzalez de Bulnes
- Dirección: Avda. Puerta de Hierro, nº12, local 10. 28040 MADRID
- Teléfono: 91 3474022
- e-mail: email@example.com